Invention Grant
- Patent Title: Nucleic acid molecules encoding beta-like glycoprotein hormone polypeptide and heterodimer thereof
- Patent Title (中): 编码β样糖蛋白激素多肽的核酸分子及其异二聚体
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Application No.: US12072822Application Date: 2008-02-27
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Publication No.: US07883868B2Publication Date: 2011-02-08
- Inventor: Christopher J. R. Paszty
- Applicant: Christopher J. R. Paszty
- Applicant Address: US CA Thousand Oaks
- Assignee: Amgen Inc.
- Current Assignee: Amgen Inc.
- Current Assignee Address: US CA Thousand Oaks
- Agent John A. Lamerdin
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C12N1/21 ; C12N15/16 ; C07K14/59 ; C12N15/74 ; A61K38/24
Abstract:
Novel β10 polypeptides and heterodimers thereof, and nucleic acid molecules encoding the same are disclosed. The invention also provides vectors, host cells, selective binding agents, and methods for producing β10 polypeptides and heterodimeric forms thereof, specifically α2/β10. Also provided for are methods for the treatment, diagnosis, amelioration, or prevention of diseases with β10 polypeptides and α2/β10 heterodimers or their respective binding agents.
Public/Granted literature
- US20080166768A1 Nucleic acid molecules encoding beta-like glycoprotein hormone polypeptide and heterodimer thereof Public/Granted day:2008-07-10
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