Invention Grant
US07883867B1 Solubilization and purification of a target protein fused to a mutant maltose-binding protein
有权
与突变体麦芽糖结合蛋白融合的目标蛋白质的溶解和纯化
- Patent Title: Solubilization and purification of a target protein fused to a mutant maltose-binding protein
- Patent Title (中): 与突变体麦芽糖结合蛋白融合的目标蛋白质的溶解和纯化
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Application No.: US12857177Application Date: 2010-08-16
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Publication No.: US07883867B1Publication Date: 2011-02-08
- Inventor: Paul Riggs , Pei-Chung Hsieh , Iris Walker , Paul A. Colussi , Mehul Ganatra , Christopher H. Taron
- Applicant: Paul Riggs , Pei-Chung Hsieh , Iris Walker , Paul A. Colussi , Mehul Ganatra , Christopher H. Taron
- Applicant Address: US MA Ipswich
- Assignee: New England Biolabs, Inc.
- Current Assignee: New England Biolabs, Inc.
- Current Assignee Address: US MA Ipswich
- Agent Harriet M. Strimpel
- Main IPC: C12N15/00
- IPC: C12N15/00 ; C12N1/20 ; C12P21/06
Abstract:
Methods and compositions are provided for increasing at least one of: (i) binding affinity of a target protein for a maltodextrin substrate and/or (ii) solubility of a target protein. The methods and compositions relate to a modified maltose-binding protein.
Public/Granted literature
- US20110020911A1 SOLUBILIZATION AND PURIFICATION OF A TARGET PROTEIN FUSED TO A MUTANT MALTOSE-BINDING PROTEIN Public/Granted day:2011-01-27
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