Invention Grant
- Patent Title: Antigen constructs useful in the detection and differentiation of antibodies to HIV
- Patent Title (中): 用于HIV抗体检测和分化的抗原构建体
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Application No.: US12574407Application Date: 2009-10-06
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Publication No.: US07883845B2Publication Date: 2011-02-08
- Inventor: John R. Hackett, Jr. , Julie Yamaguchi , Alan M. Golden , Catherine A. Brennan , Robert K. Hickman , Sushil G. Devare
- Applicant: John R. Hackett, Jr. , Julie Yamaguchi , Alan M. Golden , Catherine A. Brennan , Robert K. Hickman , Sushil G. Devare
- Applicant Address: US IL Abbott Park
- Assignee: Abbott Laboratories
- Current Assignee: Abbott Laboratories
- Current Assignee Address: US IL Abbott Park
- Agent Audrey L. Bartnicki; Cheryl L. Becker; Lisa V. Mueller
- Main IPC: C12Q1/70
- IPC: C12Q1/70 ; C07K14/005 ; C07K14/16
Abstract:
Isolated HIV-1 Group O env polypeptides obtained from the HIV-1 isolate HAM112 are claimed, as well as (a) antigen constructs comprising fusions of one or more of each of HIV-1 Group O env polypeptides and HIV-1 Group M env polypeptide and (b) further antigen constructs containing additional Group O sequences and especially the gp41 IDR of isolate HAM112. Also claimed are polynucleotide sequences encoding the above, expression vectors comprising the same, host cells transformed thereby, and immunoassay methods and kits utilizing the antigen constructs of the invention.
Public/Granted literature
- US20100035237A1 NOVEL ANTIGEN CONSTRUCTS USEFUL IN THE DETECTION AND DIFFERENTIATION OF ANTIBODIES TO HIV Public/Granted day:2010-02-11
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