Invention Grant
US07863460B2 Process for producing 1-substituted-3-fluoroalkylpyrazole-4-carboxylate
有权
1-取代-3-氟代烷基吡唑-4-羧酸酯的制备方法
- Patent Title: Process for producing 1-substituted-3-fluoroalkylpyrazole-4-carboxylate
- Patent Title (中): 1-取代-3-氟代烷基吡唑-4-羧酸酯的制备方法
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Application No.: US11884665Application Date: 2006-02-23
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Publication No.: US07863460B2Publication Date: 2011-01-04
- Inventor: Hidenori Aihara , Wakako Yokota , Tetsu Yamakawa , Kenji Hirai
- Applicant: Hidenori Aihara , Wakako Yokota , Tetsu Yamakawa , Kenji Hirai
- Applicant Address: JP Kanagawa JP Tokyo
- Assignee: Sagami Chemical Research Center,Japan Finechem Company, Inc.
- Current Assignee: Sagami Chemical Research Center,Japan Finechem Company, Inc.
- Current Assignee Address: JP Kanagawa JP Tokyo
- Agency: Sughrue Mion, PLLC
- Priority: JP2005-052004 20050225; JP2005-052006 20050225
- International Application: PCT/JP2006/303269 WO 20060223
- International Announcement: WO2006/090778 WO 20060831
- Main IPC: C07D231/14
- IPC: C07D231/14

Abstract:
In a process for producing 1-substituted-3-fluoroalkyl-pyrazole-4-carboxylate (3) by a reaction of 2-alkoxymethylenefluoroacylacetate (1) and hydrazine (2), the reaction is conducted in the presence of a base and water, to produce 1-substituted-3-fluoroalkylpyrazole-4-carboxylate (3) with high selectivity and yield. This novel process enables to produce 1-substituted-3-fluoroalkylpyrazole-4-carboxylate (3), which is useful as an intermediate for pharmaceuticals and agrochemicals, with high selectivity and yield by simple and safe operations.
Public/Granted literature
- US20080154045A1 Process for Producing 1-Substituted-3-Fluoroalkylpyrazole-4-Carboxylate Public/Granted day:2008-06-26
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