Invention Grant
US07846962B2 3-3-di-substituted-oxindoles as inhibitors of translation initiation
有权
3-3-二取代羟吲哚作为翻译起始的抑制剂
- Patent Title: 3-3-di-substituted-oxindoles as inhibitors of translation initiation
- Patent Title (中): 3-3-二取代羟吲哚作为翻译起始的抑制剂
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Application No.: US12368588Application Date: 2009-02-10
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Publication No.: US07846962B2Publication Date: 2010-12-07
- Inventor: José A. Halperin , Amarnath Natarajan , Huseyin Aktas , Yun-Hua Fan , Han Chen
- Applicant: José A. Halperin , Amarnath Natarajan , Huseyin Aktas , Yun-Hua Fan , Han Chen
- Applicant Address: US MA Cambridge
- Assignee: President and Fellows of Harvard College
- Current Assignee: President and Fellows of Harvard College
- Current Assignee Address: US MA Cambridge
- Main IPC: A61K31/404
- IPC: A61K31/404 ; C07D209/34
Abstract:
Compositions and methods for inhibiting translation using 3-(5-tert-Butyl-2-Hydroxy-phenyl)-3-phenyl-1,3-dihydro-indol-2-one and/or its derivatives are provided. Compositions, methods and kits for treating (1) cellular proliferative disorders, (2) non-proliferative, degenerative disorders, (3) viral infections, and/or (4) disorders associated with viral infections, using 3-(5-tert-butyl-2-hydroxy-phenyl)-3-phenyl-1,3-dihydro-indol-2-one and/or its derivatives are described.
Public/Granted literature
- US20090299058A1 3-3-DI-SUBSTITUTED-OXINDOLES AS INHIBITORS OF TRANSLATION INITIATION Public/Granted day:2009-12-03
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