Invention Grant
- Patent Title: Anti-α2 integrin antibodies and their uses
- Patent Title (中): 抗α2整合素抗体及其用途
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Application No.: US11601595Application Date: 2006-11-17
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Publication No.: US07807794B2Publication Date: 2010-10-05
- Inventor: Elias Lazarides , Catherine Mary Woods , Mark Bernard
- Applicant: Elias Lazarides , Catherine Mary Woods , Mark Bernard
- Applicant Address: CH La Chaux-De-Fonds
- Assignee: Glenmark Pharmaceuticals S.A.
- Current Assignee: Glenmark Pharmaceuticals S.A.
- Current Assignee Address: CH La Chaux-De-Fonds
- Agency: K&L Gates LLP
- Main IPC: C07K16/28
- IPC: C07K16/28 ; C07K16/46
Abstract:
The invention relates to anti-α2 integrin antibodies and their uses. Humanized antibodies are disclosed that bind to the I domain of α2 integrin and inhibit the interaction of α2β1 integrin with collagen. Also disclosed are therapeutic uses of anti-α2 integrin antibodies in treating α2β1-mediated disorders, including anti-α2 integrin antibodies that bind to α2 integrin without activating platelets.
Public/Granted literature
- US20070128190A1 Anti-alpha2 integrin antibodies and their uses Public/Granted day:2007-06-07
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