Invention Grant
- Patent Title: Pan-antagonists for the androgen receptor and androgen associated with anti-androgen withdrawal
- Patent Title (中): 雄激素受体拮抗剂和与雄激素相关的雄激素停止
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Application No.: US12466805Application Date: 2009-05-15
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Publication No.: US07807713B2Publication Date: 2010-10-05
- Inventor: John Tze-tzun Koh , Paula Lynn McGinley , Hongmu Pan
- Applicant: John Tze-tzun Koh , Paula Lynn McGinley , Hongmu Pan
- Applicant Address: US DE Newark
- Assignee: University of Delaware
- Current Assignee: University of Delaware
- Current Assignee Address: US DE Newark
- Agency: Potter Anderson & Corroon LLP
- Main IPC: A61K31/277
- IPC: A61K31/277 ; A61P35/00 ; C07C317/32
Abstract:
Disclosed herein are novel antagonists of the androgen receptor and androgen receptor mutations associated with clinical failure of currently prescribed anti-androgens and use of said antagonists in the treatment of conditions associated with inappropriate activation of the androgen receptor.
Public/Granted literature
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