Invention Grant
- Patent Title: Antidiabetic oxazolidinediones and thiazolidinediones
- Patent Title (中): 抗糖尿病恶唑烷二酮类和噻唑烷二酮类
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Application No.: US11922628Application Date: 2006-06-30
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Publication No.: US07807692B2Publication Date: 2010-10-05
- Inventor: James F. Dropinski , Peter T. Meinke , Guo Q. Shi , Yong Zhang
- Applicant: James F. Dropinski , Peter T. Meinke , Guo Q. Shi , Yong Zhang
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Janet E. Fair; John C. Todaro
- International Application: PCT/US2006/026047 WO 20060630
- International Announcement: WO2007/008501 WO 20070118
- Main IPC: A61K31/47
- IPC: A61K31/47 ; A61K31/42 ; A61K31/44 ; C07D413/00 ; C07D215/02 ; C07D263/00
Abstract:
Phenoxyphenyl and phenoxybenzyl oxazolidine-2,4-diones and thiazolidine-2,4-diones are agonists or partial agonists of PPAR gamma and are useful in the treatment and control of hyperglycemia that is symptomatic of type II diabetes, as well as dyslipidemia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, and obesity that are often associated with type 2 diabetes.
Public/Granted literature
- US20100168164A1 Antidiabetic Oxazolidinediones and Thiazolidinediones Public/Granted day:2010-07-01
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