Invention Grant
- Patent Title: Compounds that are ERK inhibitors
- Patent Title (中): ERK抑制剂的化合物
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Application No.: US11705709Application Date: 2007-02-13
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Publication No.: US07807672B2Publication Date: 2010-10-05
- Inventor: Yongqi Deng , Gerald W. Shipps, Jr. , Alan Cooper , Yang Nan , Tong Wang , M. Arshad Siddiqui , Hugh Zhu , Robert Sun , Joseph M. Kelly , Ronald Doll , Jagdish Desai , James J-S Wang , Youhao Dong , Vincent Madison , Li Xiao , Alan Hruza , Neng-Yang Shih
- Applicant: Yongqi Deng , Gerald W. Shipps, Jr. , Alan Cooper , Yang Nan , Tong Wang , M. Arshad Siddiqui , Hugh Zhu , Robert Sun , Joseph M. Kelly , Ronald Doll , Jagdish Desai , James J-S Wang , Youhao Dong , Vincent Madison , Li Xiao , Alan Hruza , Neng-Yang Shih
- Applicant Address: US NJ Kenilworth
- Assignee: Schering Corporation
- Current Assignee: Schering Corporation
- Current Assignee Address: US NJ Kenilworth
- Agent Henry C. Jeanette
- Main IPC: A61K31/506
- IPC: A61K31/506 ; A61K31/5377 ; A61K31/4025 ; A61K31/496 ; C07D401/06 ; C07D401/12 ; C07D401/14 ; C07D403/12 ; C07D405/12 ; C07D413/12 ; C07D417/06 ; C07D417/12
Abstract:
Disclosed are the ERK inhibitors of formula 1.0: and the pharmaceutically acceptable salts and solvates thereof. Q is a piperidine or piperazine ring that can have a bridge or a fused ring. The piperidine ring can have a double bond in the ring. All other substituents are as defined herein. Also disclosed are methods of treating cancer using the compounds of formula 1.0.
Public/Granted literature
- US20070232610A1 Novel compounds that are ERK inhibitors Public/Granted day:2007-10-04
Information query
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