Invention Grant
- Patent Title: Modulation of forkhead box O1A expression
- Patent Title (中): 叉头盒O1A表达式的调制
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Application No.: US11739017Application Date: 2007-04-23
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Publication No.: US07807649B2Publication Date: 2010-10-05
- Inventor: Kenneth W. Dobie , Sanjay Bhanot , Murielle Veniant-Ellison , Richard A. Lindberg , John R. Shutter , Robert McKay , Sanjay K. Pandey
- Applicant: Kenneth W. Dobie , Sanjay Bhanot , Murielle Veniant-Ellison , Richard A. Lindberg , John R. Shutter , Robert McKay , Sanjay K. Pandey
- Applicant Address: US CA Carlsbad
- Assignee: Isis Pharmaceuticals, Inc.
- Current Assignee: Isis Pharmaceuticals, Inc.
- Current Assignee Address: US CA Carlsbad
- Agency: Isis Pharmaceuticals, Inc. Patent Dept.
- Main IPC: A61K48/00
- IPC: A61K48/00

Abstract:
Antisense compounds, compositions and methods are provided for modulating the expression of forkhead box O1A. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding forkhead box O1A. Methods of using these compounds for modulation of forkhead box O1A expression and for treatment of diseases associated with expression of forkhead box O1A are provided, in particular, for methods of treating diabetes.
Public/Granted literature
- US20080153767A1 MODULATION OF FORKHEAD BOX O1A EXPRESSION Public/Granted day:2008-06-26
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