Invention Grant
- Patent Title: Methods of promoting growth of muscle tissue using ALK7
- Patent Title (中): 使用ALK7促进肌肉组织生长的方法
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Application No.: US12288291Application Date: 2008-10-17
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Publication No.: US07807631B2Publication Date: 2010-10-05
- Inventor: John Knopf , Jasbir Seehra
- Applicant: John Knopf , Jasbir Seehra
- Applicant Address: US MA Cambridge
- Assignee: Acceleron Pharma Inc.
- Current Assignee: Acceleron Pharma Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Ropes & Gray LLP
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K38/16 ; A61K38/17
Abstract:
The invention relates to ALK7 soluble receptors and their uses as antagonists of the function of certain ligands such as GDF-8 (Myostatin) and GDF-11. The ALK7 soluble receptor of the invention is useful as antagonists of GDF-8 and GDF-11 in the treatment of neuronal diseases or conditions such as stroke, spinal cord injury, and all peripheral nerve diseases. The ALK7 soluble receptor of the invention is also useful as GH (growth hormone) equivalent, and for increasing muscle mass.
Public/Granted literature
- US20090098114A1 ALK7 and myostatin inhibitors and uses thereof Public/Granted day:2009-04-16
Information query
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