Invention Grant
- Patent Title: Use of phytoene synthase for controlling transgene escape
- Patent Title (中): 使用八氢番茄红素合酶控制转基因逃逸
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Application No.: US11632397Application Date: 2005-07-05
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Publication No.: US07790950B2Publication Date: 2010-09-07
- Inventor: Viktor Kuvshinov , Kimmo Koivu , Anne Kanerva , Andrei Anissimov
- Applicant: Viktor Kuvshinov , Kimmo Koivu , Anne Kanerva , Andrei Anissimov
- Agency: Dodds & Associates
- Agent Leea S. Somersalo; John Dodds
- International Application: PCT/FI2005/050268 WO 20050705
- International Announcement: WO2006/005807 WO 20060119
- Main IPC: C12N15/82
- IPC: C12N15/82 ; C12N15/31 ; C12N15/52 ; A01N45/02

Abstract:
The present invention is related to a recoverable block of function (RBF) system for controlling transgene escape and transgene containment in plants. The RBF-system comprises at least one blocking construct (BC), wherein the BC comprises as the blocking gene a nucleotide sequence or crtB gene encoding phytoene synthase, which is used alone or in combination with other BCs. The crtB gene expresses under the control of a germination specific promoter or a promoter constitutively repressed by a Recovering construct (RC) and blocks the germination of a transgenic seed. The blocked germination is recoverable by a user controlled intervention including addition of an effective amount of gibberellin and sugar and may involve so called recovering constructs (RCs), wherein the recovering gene may encode ent-copalyl diphosphate synthase or ent-kaurene synthase.
Public/Granted literature
- US20080085996A1 Use Of Phytoene Synthase For Controlling Transgene Escape Public/Granted day:2008-04-10
Information query
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