Invention Grant
- Patent Title: Acylaminopiperidine compound
- Patent Title (中): 酰胺基哌啶化合物
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Application No.: US12294145Application Date: 2007-03-23
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Publication No.: US07790884B2Publication Date: 2010-09-07
- Inventor: Toru Kontani , Noriyuki Kawano , Naoyuki Masuda , Koji Kato , Hiroshi Nagata , Hiroshi Inami , Tadashi Terasaka , Kazuhiro Yokoyama , Takahiro Miyazaki
- Applicant: Toru Kontani , Noriyuki Kawano , Naoyuki Masuda , Koji Kato , Hiroshi Nagata , Hiroshi Inami , Tadashi Terasaka , Kazuhiro Yokoyama , Takahiro Miyazaki
- Applicant Address: JP Tokyo
- Assignee: Astellas Pharma Inc.
- Current Assignee: Astellas Pharma Inc.
- Current Assignee Address: JP Tokyo
- Agency: Sughrue Mion, PLLC
- Priority: JP2006-084037 20060324
- International Application: PCT/JP2007/055943 WO 20070323
- International Announcement: WO2007/111227 WO 20071004
- Main IPC: C07D473/34
- IPC: C07D473/34

Abstract:
To provide a compound which has an excellent activity to modulate the functions of CCR4 or TARC and/or MDC and can be used for the prevention and/or treatment of various inflammatory diseases, allergic diseases, autoimmune diseases and the like.An acylaminopiperidine compound represented by the formula (I) or a pharmaceutically acceptable salt thereof. [Symbols in the formula represent the following meanings; A: a single bond or C1-C6 alkylene, R1: phenyl which may be substituted, etc., R2: —H or C1-C6 alkyl, R3: —H, C1-C6 alkyl or C3-C8 cycloalkyl, R4: pyrrolidin-2-yl which may be substituted, etc., and D: benzene ring or pyrazole ring].
Public/Granted literature
- US20090131666A1 ACYLAMINOPIPERIDINE COMPOUND Public/Granted day:2009-05-21
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