Invention Grant
- Patent Title: Bacterial ion channel
- Patent Title (中): 细菌离子通道
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Application No.: US10494783Application Date: 2002-11-05
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Publication No.: US07790845B2Publication Date: 2010-09-07
- Inventor: David Clapham , Dejian Ren
- Applicant: David Clapham , Dejian Ren
- Applicant Address: US MA Boston
- Assignee: Children's Medical Center Corporation
- Current Assignee: Children's Medical Center Corporation
- Current Assignee Address: US MA Boston
- Agency: Nixon Peabody LLP
- International Application: PCT/US02/35395 WO 20021105
- International Announcement: WO03/040323 WO 20030515
- Main IPC: C07K14/195
- IPC: C07K14/195
Abstract:
The present invention relates to a functionally expressed bacterial voltage-sensitive ion-selective channel. The novel channel can be used in conjunction with mammalian ion channel pore-containing regions in assays for screening for compounds that modulate activity of the channel. One bacterial ion channel of the present invention, called NaChBac, is derived from Bacillus halodurans (GenBank#BAB05220 (8)).
Public/Granted literature
- US20050101767A1 Bacterial ion channel and a method for screening ion channel modulators Public/Granted day:2005-05-12
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