Invention Grant
US07790733B2 8-alkoxy or cycloalkoxy-4-methyl-3,4-dihydro-quinazolin-2-ylamines
失效
8-烷氧基或环烷氧基-4-甲基-3,4-二氢 - 喹唑啉-2-基胺
- Patent Title: 8-alkoxy or cycloalkoxy-4-methyl-3,4-dihydro-quinazolin-2-ylamines
- Patent Title (中): 8-烷氧基或环烷氧基-4-甲基-3,4-二氢 - 喹唑啉-2-基胺
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Application No.: US11472084Application Date: 2006-06-21
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Publication No.: US07790733B2Publication Date: 2010-09-07
- Inventor: Alexander Alanine , Luca Claudio Gobbi , Sabine Kolczewski , Thomas Luebbers , Jens-Uwe Peters , Lucinda Steward
- Applicant: Alexander Alanine , Luca Claudio Gobbi , Sabine Kolczewski , Thomas Luebbers , Jens-Uwe Peters , Lucinda Steward
- Applicant Address: US NJ Nutley
- Assignee: Hoffman-La Roche Inc.
- Current Assignee: Hoffman-La Roche Inc.
- Current Assignee Address: US NJ Nutley
- Agent George W. Johnston; Patricia S. Rocha-Tramaloni; Kimberly J. Prior
- Priority: EP05105699 20050627
- Main IPC: A61K31/517
- IPC: A61K31/517 ; C07D239/84

Abstract:
The present invention relates to compounds of formula wherein R1, R2, R3, and n are as described in the specification and pharmaceutically acceptable acid addition salts thereof. The compounds of formula I can be used for the treatment of 5-HT5A receptor antagonists related diseases, which include depression, anxiety disorders, schizophrenia, panic disorders, agoraphobia, social phobia, obsessive compulsive disorders, post-traumatic stress disorders, pain, memory disorders, disorders of eating behaviors, sexual dysfunction, sleep disorders, withdrawal from abuse of drugs, motor disorders such as Parkinson's disease, dementia in Parkinson's disease, neuroleptic-induced Parkinsonism and tardive dyskinesias, as well as other psychiatric disorders and gastrointestinal disorders such as irritable bowel syndrome.
Public/Granted literature
- US20060293350A1 8-Alkoxy or cycloalkoxy-4-methyl-3,4-dihydro-quinazolin-2-ylamines Public/Granted day:2006-12-28
Information query
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