Invention Grant
US07790732B2 5-Chloro-4-alkyl-3,4-dihydro-quinazolin-2-ylamine derivatives
失效
5-氯-4-烷基-3,4-二氢 - 喹唑啉-2-基胺衍生物
- Patent Title: 5-Chloro-4-alkyl-3,4-dihydro-quinazolin-2-ylamine derivatives
- Patent Title (中): 5-氯-4-烷基-3,4-二氢 - 喹唑啉-2-基胺衍生物
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Application No.: US11472081Application Date: 2006-06-21
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Publication No.: US07790732B2Publication Date: 2010-09-07
- Inventor: Alexander Alanine , Luca Claudio Gobbi , Sabine Kolczewski , Thomas Luebbers , Jens-Uwe Peters , Lucinda Steward
- Applicant: Alexander Alanine , Luca Claudio Gobbi , Sabine Kolczewski , Thomas Luebbers , Jens-Uwe Peters , Lucinda Steward
- Applicant Address: US NJ Nutley
- Assignee: Hoffman-La Roche Inc.
- Current Assignee: Hoffman-La Roche Inc.
- Current Assignee Address: US NJ Nutley
- Agent George W. Johnston; Patricia S. Rocha-Tramaloni; Kimberly J. Prior
- Priority: EP05105697 20050627
- Main IPC: A61K31/517
- IPC: A61K31/517 ; C07D239/84
Abstract:
The present invention relates to compounds of formula I wherein R1, R2, R3 are as described in the specification and pharmaceutically acceptable acid addition salts and tautomers thereof. Compounds of formula I have good activity on the 5-HT5A receptor. Therefore, the invention provides a method for treating diseases related to this receptor, for example, anxiety, depression, sleep disorders and schizophrenia.
Public/Granted literature
- US20060293349A1 5-Chloro-4-alkyl-3,4-dihydro-quinazolin-2-ylamine derivatives Public/Granted day:2006-12-28
Information query
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