Invention Grant
- Patent Title: Monocyclic and bicyclic compounds and methods of use
- Patent Title (中): 单环和双环化合物及其使用方法
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Application No.: US11504215Application Date: 2006-08-14
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Publication No.: US07790726B2Publication Date: 2010-09-07
- Inventor: Penglie Zhang , Andrew M. K. Pennell , John J. Kim Wright , Lianfa Li , Edward J. Sullivan , Wei Chen , Kevin Lloyd Greenman
- Applicant: Penglie Zhang , Andrew M. K. Pennell , John J. Kim Wright , Lianfa Li , Edward J. Sullivan , Wei Chen , Kevin Lloyd Greenman
- Applicant Address: US CA Mountain View
- Assignee: Chemocentryx, Inc.
- Current Assignee: Chemocentryx, Inc.
- Current Assignee Address: US CA Mountain View
- Agency: Townsend and Townsend and Crew LLP
- Main IPC: C07D263/58
- IPC: C07D263/58 ; C07D413/06 ; A61K31/496 ; C07D401/06 ; C07D498/04
Abstract:
Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are generally monocyclic and bicyclic compounds and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated diseases, and as controls in assays for the identification of competitive CCR1 antagonists.
Public/Granted literature
- US20070066583A1 Monocyclic and bicyclic compounds and methods of use Public/Granted day:2007-03-22
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