知搜-全球专利检索

  1. Login
  2. Sign Up
Invention Grant
US07790720B2 Compounds comprising an oxazole or thiazole moiety, processes for making them, and their uses 失效
包含恶唑或噻唑部分的化合物，其制备方法及其用途

Compounds comprising an oxazole or thiazole moiety, processes for making them, and their uses
Abstract:
The present invention relates to compounds comprising an oxazole or thiazole moiety of formula (I), processes for preparing them, pharmaceutical compositions comprising said compounds and their uses as H3-receptor ligands, Formula (I), wherein, A1 is CH, C(alkyl), C-halogen or N; R1 is hydrogen, halogen, C1-6 alkyl or alkoxy; R2 is, Formula (II′), A3 is O or S; R3 is hydrogen, halogen, C1-6 alkyl or alkoxy; R4 is hydrogen, halogen, C1-6 alkyl, alkoxy or —O-L; R5 is hydrogen or —O-L, wherein L is an aminoalkyl group and at least one of R4 and R5 should be —O-L.
Abstract(Chinese):

本发明涉及包含式（I）的恶唑或噻唑部分的化合物，其制备方法，包含所述化合物的药物组合物及其用作H3受体配体的式（I），其中，A 1为CH，C（ 烷基），C-卤素或N; R1是氢，卤素，C1-6烷基或烷氧基; R2为式（II'），A3为O或S; R3是氢，卤素，C1-6烷基或烷氧基; R4是氢，卤素，C1-6烷基，烷氧基或-O-L; R5是氢或-O-L，其中L是氨基烷基，R4和R5中的至少一个应为-O-L。

Public/Granted literature
Information query
Espacenet
Patent Agency Ranking
0/0