Invention Grant
- Patent Title: Glucose sensitive regulator of insulin transcription
- Patent Title (中): 葡萄糖敏感的胰岛素转录调节因子
-
Application No.: US09972916Application Date: 2001-10-10
-
Publication No.: US07790690B2Publication Date: 2010-09-07
- Inventor: Peter M. Thulé
- Applicant: Peter M. Thulé
- Applicant Address: US DC Washington
- Assignee: U.S. Department of Veterans Affairs
- Current Assignee: U.S. Department of Veterans Affairs
- Current Assignee Address: US DC Washington
- Agent Dinesh Agarwal, P.C.
- Main IPC: A61K31/70
- IPC: A61K31/70
Abstract:
A glucose sensitive regulator of insulin transcription includes a glucose response element (GIRE) of a liver-pyruvate (L-PK) gent promoter, and an insulin-sensitive element of an insulin-like growth factor binding protein-1 (IGFBP-1) basal promoter. The transcriptional activity of the regulator is stimulated by glucose and inhibited by insulin.
Public/Granted literature
- US20020107198A1 Glucose sensitive regulator of insulin transcription Public/Granted day:2002-08-08
Information query
