Invention Grant
US07790445B2 Polypeptide having an improved cytosine deaminase activity 有权
具有改进的胞嘧啶脱氨酶活性的多肽

  • Patent Title: Polypeptide having an improved cytosine deaminase activity
  • Patent Title (中): 具有改进的胞嘧啶脱氨酶活性的多肽
  • Application No.: US10565230
    Application Date: 2004-06-29
  • Publication No.: US07790445B2
    Publication Date: 2010-09-07
  • Inventor: Philippe Erbs
  • Applicant: Philippe Erbs
  • Applicant Address: FR Illkirch Graffenstaden Cedex
  • Assignee: Transgene S.A.
  • Current Assignee: Transgene S.A.
  • Current Assignee Address: FR Illkirch Graffenstaden Cedex
  • Agency: Buchanan Ingersoll & Rooney PC
  • Priority: EP03360087 20030721
  • International Application: PCT/IB2004/002505 WO 20040629
  • International Announcement: WO2005/007857 WO 20050127
  • Main IPC: C12N15/85
  • IPC: C12N15/85 C12N15/54 C12N15/55 C12N15/62
Polypeptide having an improved cytosine deaminase activity
Abstract:
The present invention relates to a polypeptide possessing a CDase activity, characterized in that it is derived from a native CDase by addition of an amino acid sequence with the proviso that said polypeptide has no UPRtase or Thymidine Kinase activity.
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