Invention Grant
- Patent Title: Immunogenic composition of a homogeneous live attenuated human rotavirus population
- Patent Title (中): 均质减毒人轮状病毒群体的免疫原性组成
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Application No.: US11875286Application Date: 2007-10-19
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Publication No.: US07790180B2Publication Date: 2010-09-07
- Inventor: Brigitte Desiree Alberte Colau , Francoise Denamur , Isabelle Knott , Annick Poliszczak , Georges Thiry , Vincent Vande Velde
- Applicant: Brigitte Desiree Alberte Colau , Francoise Denamur , Isabelle Knott , Annick Poliszczak , Georges Thiry , Vincent Vande Velde
- Applicant Address: BE Rixensart
- Assignee: Glaxosmithkline Biologicals SA
- Current Assignee: Glaxosmithkline Biologicals SA
- Current Assignee Address: BE Rixensart
- Agency: Glaxosmithkline-Global Patents-US
- Agent Gwynedd Warren
- Priority: GB9919468.0 19990817; GB9927336.9 19991118
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K39/12 ; A61K39/15
Abstract:
The invention provides an attenuated rotavirus population comprising a single variant or substantially a single variant which is defined by a nucleotide sequence encoding at least one of the major viral proteins designated as VP4 and VP7. The invention particularly provides a rotavirus population designated as P43. The invention further provides a novel formulation for a rotavirus vaccine which is in the form of a quick dissolving tablet for immediate dissolution when placed on the tongue.
Public/Granted literature
- US20080057082A1 VACCINE Public/Granted day:2008-03-06
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