Invention Grant
US07790159B2 Methods, combinations and kits for treating viral infections using immunoconjugates and antibodies to aminophospholipids
有权
使用免疫缀合物和氨基磷脂抗体治疗病毒感染的方法，组合和试剂盒
- Patent Title: Methods, combinations and kits for treating viral infections using immunoconjugates and antibodies to aminophospholipids
- Patent Title (中): 使用免疫缀合物和氨基磷脂抗体治疗病毒感染的方法，组合和试剂盒
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Application No.: US10642119Application Date: 2003-08-15
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Publication No.: US07790159B2Publication Date: 2010-09-07
- Inventor: Philip E. Thorpe , M. Melina Soares , Sophia Ran
- Applicant: Philip E. Thorpe , M. Melina Soares , Sophia Ran
- Applicant Address: US TX Austin
- Assignee: Board of Regents, The University of Texas System
- Current Assignee: Board of Regents, The University of Texas System
- Current Assignee Address: US TX Austin
- Agent Shelley P. M. Fussey
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K39/00
Abstract:
Disclosed are surprising discoveries concerning the role of anionic phospholipids and aminophospholipids in tumor vasculature and in viral entry and spread, and compositions and methods for utilizing these findings in the treatment of cancer and viral infections. Also disclosed are advantageous antibody, immunoconjugate and duramycin-based compositions and combinations that bind and inhibit anionic phospholipids and aminophospholipids, for use in the safe and effective treatment of cancer, viral infections and related diseases.
Public/Granted literature
- US20040213779A1 Methods for treating viral infections using immunoconjugates to aminophospholipids Public/Granted day:2004-10-28
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