Invention Grant
US07767679B2 Sulfonylamino-derivatives as novel inhibitors of histone deacetylase
有权
磺酰氨基衍生物作为组蛋白脱乙酰酶的新型抑制剂
- Patent Title: Sulfonylamino-derivatives as novel inhibitors of histone deacetylase
- Patent Title (中): 磺酰氨基衍生物作为组蛋白脱乙酰酶的新型抑制剂
-
Application No.: US10507159Application Date: 2003-03-11
-
Publication No.: US07767679B2Publication Date: 2010-08-03
- Inventor: Kristof Van Emelen , Leo Jacobus Jozef Backx , Sven Franciscus Anna Van Brandt , Patrick René Angibaud , Isabelle Noëlle Constance Pilatte , Marc Gustaaf Celine Verdonck , Hans Louis Jos De Winter , Jimmy Arnold Viviane Van heusden
- Applicant: Kristof Van Emelen , Leo Jacobus Jozef Backx , Sven Franciscus Anna Van Brandt , Patrick René Angibaud , Isabelle Noëlle Constance Pilatte , Marc Gustaaf Celine Verdonck , Hans Louis Jos De Winter , Jimmy Arnold Viviane Van heusden
- Applicant Address: BE Beerse
- Assignee: Janssen Pharmaceutica N.V.
- Current Assignee: Janssen Pharmaceutica N.V.
- Current Assignee Address: BE Beerse
- Agency: Patton Boggs LLP
- Priority: WOPCT/EP02/14481 20021218
- International Application: PCT/EP03/02517 WO 20030311
- International Announcement: WO03/076401 WO 20030918
- Main IPC: A61K31/506
- IPC: A61K31/506 ; C07D403/04
Abstract:
This invention comprises the novel compounds of formula (I) wherein n, m, t, R1, R2, R3, R4, R5, L, Q, X, Y, Z and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
Public/Granted literature
- US20050171347A1 Sulfonylamino-derivatives as novel inhibitors of histone deacetylase Public/Granted day:2005-08-04
Information query
IPC分类:
