Invention Grant
- Patent Title: Antibodies against SARS-CoV and methods of use thereof
- Patent Title (中): 针对SARS-CoV的抗体及其使用方法
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Application No.: US10997201Application Date: 2004-11-24
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Publication No.: US07750123B2Publication Date: 2010-07-06
- Inventor: Wayne Marasco , Jianhua Sui
- Applicant: Wayne Marasco , Jianhua Sui
- Applicant Address: US MA Boston
- Assignee: Dana Farber Cancer Institute, Inc.
- Current Assignee: Dana Farber Cancer Institute, Inc.
- Current Assignee Address: US MA Boston
- Agency: Mintz, Levin, Cohen, Ferris, Glovsky and Popeo P.C.
- Agent Ivor R. Elrifi; Cynthia A. Kozakiewicz
- Main IPC: C12P21/08
- IPC: C12P21/08 ; G01N33/563 ; A61K39/395 ; A61K39/00
Abstract:
The invention provides scFv antibodies and monoclonal antibodies that neutralize SARS-CoV. Also provided are methods of treating and/or preventing a coronavirus-related disease or disorder such as SARS. The invention also provides methods of vaccinating a patient against SARS-CoV. Also provided are methods of diagnosing coronavirus-related diseases or disorders and methods of detecting the presence of a coronavirus in a sample. The invention additionally provides methods of screening for compounds that modulate the binding of SARS-CoV and the SARS-CoV receptor ACE2 as well as for compounds useful to treat SARS-CoV-related diseases or disorders.
Public/Granted literature
- US20050249739A1 Antibodies against SARS-CoV and methods of use thereof Public/Granted day:2005-11-10
Information query
