Invention Grant
- Patent Title: Compounds and compositions as PPAR modulators
- Patent Title (中): 化合物和组合物作为PPAR调节剂
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Application No.: US11815096Application Date: 2006-02-03
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Publication No.: US07750032B2Publication Date: 2010-07-06
- Inventor: Christopher Cow , Robert Epple , Xing Wang , Yongping Xie , Hans Martin Seidel
- Applicant: Christopher Cow , Robert Epple , Xing Wang , Yongping Xie , Hans Martin Seidel
- Applicant Address: BM Hamilton
- Assignee: IRM LLC
- Current Assignee: IRM LLC
- Current Assignee Address: BM Hamilton
- Agency: Genomics Institute of the Novartis Research Foundation
- Agent Scott W. Reid; D. Phil
- International Application: PCT/US2006/003924 WO 20060203
- International Announcement: WO2006/084176 WO 20060810
- Main IPC: C07D213/64
- IPC: C07D213/64 ; C07D265/30 ; C07D233/64 ; C07D231/12 ; C07D413/10 ; C07D401/04 ; A61K31/4155 ; A61K31/4178 ; A61K31/4164 ; A61K31/4439 ; A61K31/5377
Abstract:
The invention provides trisubstituted pyrazoles and imidazoles of Formula I: wherein L2, q, R13, R14, R15, R16, Z1 and Z2 are as described in the Summary of the Invention; and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of the peroxisome proliferator-activated receptor (PPAR) families, particularly the activity of PPARδ.
Public/Granted literature
- US20090137591A1 COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS Public/Granted day:2009-05-28
Information query
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