Invention Grant
US07750029B2 Remedy for overactive bladder comprising acetic acid anilide derivative as the active ingredient
有权
包括醋酸苯胺衍生物作为活性成分的膀胱活动过度的补救措施
- Patent Title: Remedy for overactive bladder comprising acetic acid anilide derivative as the active ingredient
- Patent Title (中): 包括醋酸苯胺衍生物作为活性成分的膀胱活动过度的补救措施
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Application No.: US10534290Application Date: 2003-11-04
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Publication No.: US07750029B2Publication Date: 2010-07-06
- Inventor: Toshiyuki Takasu , Shuichi Sato , Masashi Ukai , Tatsuya Maruyama
- Applicant: Toshiyuki Takasu , Shuichi Sato , Masashi Ukai , Tatsuya Maruyama
- Applicant Address: JP Tokyo
- Assignee: Astellas Pharma Inc.
- Current Assignee: Astellas Pharma Inc.
- Current Assignee Address: JP Tokyo
- Agency: Sughrue Mion, PLLC
- Priority: JP2002-323792 20021107
- International Application: PCT/JP03/14065 WO 20031104
- International Announcement: WO2004/041276 WO 20040521
- Main IPC: A61K31/426
- IPC: A61K31/426 ; A61P13/10

Abstract:
(R)-2-(2-aminothiazol-4-yl)-4′-[2-[(2-hydroxy-2-phenylethyl)amino]ethyl]acetic acid anilide or its salt shows a potent bladder relaxation effect in “isolated rat bladder smooth muscle relaxation test”, dose-dependently lowers the contraction frequency of rhythmic bladder contractions in “rat rhythmic bladder contraction measurement test” and, moreover, prolongs the urination intervals in “urination functions measurement test on cyclophosphamide-induced overactive bladder model rat”. Owing to these effects, the above compound is useful as a remedy for ovaractive bladder.
Public/Granted literature
- US20060115540A1 Remedy for overactive bladder comprising acetic acid anilide derivative as the active ingredient Public/Granted day:2006-06-01
Information query
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