Invention Grant
US07750012B2 Biaryl nitrogen-heterocycle inhibitors of LTA4H for treating inflammation
失效
用于治疗炎症的LTA4H的二芳基氮杂环抑制剂
- Patent Title: Biaryl nitrogen-heterocycle inhibitors of LTA4H for treating inflammation
- Patent Title (中): 用于治疗炎症的LTA4H的二芳基氮杂环抑制剂
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Application No.: US11462278Application Date: 2006-08-03
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Publication No.: US07750012B2Publication Date: 2010-07-06
- Inventor: Vincent Sandanayaka , Jasbir Singh , Li-Ming Zhou , Mark E. Gurney
- Applicant: Vincent Sandanayaka , Jasbir Singh , Li-Ming Zhou , Mark E. Gurney
- Applicant Address: IS Reykjavik
- Assignee: deCODE genetics ehf
- Current Assignee: deCODE genetics ehf
- Current Assignee Address: IS Reykjavik
- Agency: Heslin Rothenberg Farley & Mesiti P.C.
- Main IPC: A61K31/495
- IPC: A61K31/495 ; A61K31/496 ; C07D295/15 ; C07D333/16 ; A61K31/5375 ; A61K31/5377 ; A61K31/451 ; A61K31/4523 ; C07D211/34 ; C07D211/58 ; C07D413/12
Abstract:
The present invention relates to a chemical genus of biaryl nitrogen-attached heterocycles that are inhibitors of LTA4H (leukotriene A4 hydrolase). The compounds have the general formula They are useful for the treatment and prevention and prophylaxis of inflammatory diseases and disorders.
Public/Granted literature
- US20070149544A1 BIARYL NITROGEN-HETEROCYCLE INHIBITORS OF LTA4H FOR TREATING INFLAMMATION Public/Granted day:2007-06-28
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