Invention Grant
US07728024B2 Metal salts of 2′-(1H-Tetrazol-5yl)-1.1′-biphenyl-4-carboxaldehyde
失效
2' - （1H-四唑-5-基）-1,1'-联苯-4-甲醛的金属盐
- Patent Title: Metal salts of 2′-(1H-Tetrazol-5yl)-1.1′-biphenyl-4-carboxaldehyde
- Patent Title (中): 2' - （1H-四唑-5-基）-1,1'-联苯-4-甲醛的金属盐
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Application No.: US11995240Application Date: 2006-07-10
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Publication No.: US07728024B2Publication Date: 2010-06-01
- Inventor: Gottfried Sedelmeier , Dominique Grimler
- Applicant: Gottfried Sedelmeier , Dominique Grimler
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Joseph T. Majka
- Priority: GB0514206.2 20050711
- International Application: PCT/EP2006/006730 WO 20060710
- International Announcement: WO2007/006531 WO 20070118
- Main IPC: A61K31/41
- IPC: A61K31/41 ; C07D403/00
Abstract:
The invention relates to a method or process for the manufacture of blood pressure lowering agents, such as valsartan, novel intermediates as well as process steps in said synthesis. The method or process leads via the novel intermediate salts of the formula IA, or a tautomer thereof, wherein [kat]n+ is a cation and n is 1, 2, 3, 4, 5 or 6.
Public/Granted literature
- US20080234490A1 Metal Salts of 2' - (1H-Tetrazol-5Yl) -1. 1'-Biphenyl-4-Carboxaldehyde Public/Granted day:2008-09-25
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