Invention Grant
US07709612B2 Metal chelating compositions for protein purification, detection or binding
有权
用于蛋白质纯化，检测或结合的金属螯合组合物
- Patent Title: Metal chelating compositions for protein purification, detection or binding
- Patent Title (中): 用于蛋白质纯化，检测或结合的金属螯合组合物
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Application No.: US11364928Application Date: 2006-03-01
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Publication No.: US07709612B2Publication Date: 2010-05-04
- Inventor: William K. Kappel , Vankatappa Viswanatha , Handong Li , Richard J. Mehigh , John G. Dapron
- Applicant: William K. Kappel , Vankatappa Viswanatha , Handong Li , Richard J. Mehigh , John G. Dapron
- Applicant Address: US MO St. Louis
- Assignee: Sigma-Aldrich Co.
- Current Assignee: Sigma-Aldrich Co.
- Current Assignee Address: US MO St. Louis
- Agency: Senniger Powers LLP
- Agent Jill Rogers-Manning
- Main IPC: A23J1/00
- IPC: A23J1/00 ; C07C53/00 ; C07C205/00 ; C07C229/00 ; G01N33/00 ; G01N21/75 ; C09K3/00
Abstract:
A metal chelating composition having the formula: wherein Q is a carrier; S1 is a spacer; L is -A-T-CH(X)— or —C(═O)—; A is an ether, thioether, selenoether, or amide linkage; T is a bond or substituted or unsubstituted alkyl or alkenyl; X is —(CH2)kCH3, —(CH2)kCOOH, —(CH2)kSO3H, —(CH2)kPO3H2, —(CH2)kN(J)2, or —(CH2)kP(J)2, preferably —(CH2)kCOOH or —(CH2)kSO3H; k is an integer from 0 to 2; J is hydrocarbyl or substituted hydrocarbyl; Y is —COOH, —H, —SO3H, —PO3H2, —N(J)2, or —P(J)2, preferably, —COOH; Z is —COOH, —H, —SO3H, —PO3H2, —N(J)2, or —P(J)2, preferably, —COOH; and i is an integer from 0 to 4, preferably 1 or 2.
Public/Granted literature
- US20060148090A1 Metal chelating compositions for protein purification, detection or binding Public/Granted day:2006-07-06
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