Invention Grant
- Patent Title: Adiponectin variants
- Patent Title (中): 脂联素变体
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Application No.: US11421059Application Date: 2006-05-30
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Publication No.: US07709607B2Publication Date: 2010-05-04
- Inventor: Jonathan Zalevsky , Duc-Hanh Thi Nguyen , Gregory L. Moore , Sergei A. Ezhevsky , John R. Desjarlais , Arthur J. Chirino , Darian Cash , Matthew J. Bernett
- Applicant: Jonathan Zalevsky , Duc-Hanh Thi Nguyen , Gregory L. Moore , Sergei A. Ezhevsky , John R. Desjarlais , Arthur J. Chirino , Darian Cash , Matthew J. Bernett
- Applicant Address: US CA Monrovia
- Assignee: Xencor, Inc.
- Current Assignee: Xencor, Inc.
- Current Assignee Address: US CA Monrovia
- Agency: Morgan Lewis & Bockius LLP
- Agent Robin M. Silva, Esq.; David C. Foster, Esq.
- Main IPC: C07K1/00
- IPC: C07K1/00 ; C07K14/00 ; C07K16/00 ; C07K17/00 ; A61K38/24 ; A61K38/27
Abstract:
An adiponectin variant with one or more amino acid modifications relative to a corresponding parent adiponectin, wherein the solubility of the variant is improved by at least 3-fold relative to residues 110-244 of human adiponectin.
Public/Granted literature
- US20070010659A1 Adiponectin variants Public/Granted day:2007-01-11
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