Invention Grant
- Patent Title: ActRII receptor polypeptides, methods and compositions
- Patent Title (中): ActRII受体多肽，方法和组合物
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Application No.: US11190202Application Date: 2005-07-25
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Publication No.: US07709605B2Publication Date: 2010-05-04
- Inventor: John Knopf , Jasbir Seehra
- Applicant: John Knopf , Jasbir Seehra
- Applicant Address: US MA Cambridge
- Assignee: Acceleron Pharma Inc.
- Current Assignee: Acceleron Pharma Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Ropes & Gray LLP
- Main IPC: C07K14/00
- IPC: C07K14/00
Abstract:
In certain aspects, the present invention provides compositions and methods for modulating (promoting or inhibiting) growth of a tissue, such as bone, cartilage, muscle, fat, and/or neuron. The present invention also provides methods of screening compounds that modulate activity of an ActRII protein and/or an ActRII ligand. The compositions and methods provided herein are useful in treating diseases associated with abnormal activity of an ActRII protein and/or an ActRII ligand.
Public/Granted literature
- US20060068468A1 ActRII receptor polypeptides, methods and compositions Public/Granted day:2006-03-30
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