Invention Grant
- Patent Title: Models for vaccine assessment
- Patent Title (中): 疫苗评估模型
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Application No.: US11819335Application Date: 2007-06-27
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Publication No.: US07709257B2Publication Date: 2010-05-04
- Inventor: John G. Tew , Mohey Eldin M. El Shikh , Inderpal Singh , Eric Mishkin , Donald Drake, III , Haifeng Song , William L Warren
- Applicant: John G. Tew , Mohey Eldin M. El Shikh , Inderpal Singh , Eric Mishkin , Donald Drake, III , Haifeng Song , William L Warren
- Applicant Address: US FL Orlando US VA Richmond
- Assignee: Vax Design Corp.,Virginia Commonwealth University
- Current Assignee: Vax Design Corp.,Virginia Commonwealth University
- Current Assignee Address: US FL Orlando US VA Richmond
- Agency: Roylance, Abrams
- Main IPC: C12N5/00
- IPC: C12N5/00 ; C12N5/02 ; C12N5/16
Abstract:
The present invention is directed to methods for constructing and using in vivo and in vitro models of aspects of human immunity and, in particular, construction of a human immune system model for the testing of, for example, vaccines, adjuvants, immunotherapy candidates, cosmetics, drugs, biologics and other chemicals. The present invention comprises both in vivo and in vitro models of aspects of human immunity that are useful for assessing the interaction of substances with the immune system, and thus can be used to accelerate and improve the accuracy and predictability of, for example, vaccine, drug, biologic, immunotherapy, cosmetic and chemical development. The invention is also useful for the generation of human monoclonal and polyclonal antibodies.
Public/Granted literature
- US20080008653A1 Models for vaccine assessment Public/Granted day:2008-01-10
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