A dry heat sterilization system having a housing and a number of plenums to guide the flow of hot air. Hot air is forced to flow through the plenums, the intake slide duct and into the bottom of the containers. The hot air will rise and exit from the top of the container through the exhaust slide duct. Furthermore, the external surfaces of the container are also sterilized through the use of semi-pierced duct walls with adjustable diffuser panels. Hot air will re-circulate until it reaches a pre-determined temperature. The container and its contents can be safely handled once the exhaust air blower removes hot air from the system.