A doorframe structure comprises an upper guide formed of metal plate so as to have an enclosed space extending in a longitudinal direction of the upper guide, the upper guide having a constant cross section, a weather strip channel extending in a longitudinal direction of the upper guide and fixed to the upper guide, a window glass guide, made of metal plate, arranged so as to be inclined relative to the upper guide and fixed to the upper guide at one end thereof in order to guide a window glass so as to move, and a pillar outer panel, made of metal plate, for covering, on an exterior side of a vehicle, a vehicle exterior-end surface of the upper guide, a vehicle exterior-end surface of the window glass guide and an opening formed between the upper guide and the window glass guide.