Invention Grant
- Patent Title: Hepatitis C inhibitor peptide analogs
- Patent Title (中): 丙型肝炎抑制肽类似物
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Application No.: US10595108Application Date: 2005-06-22
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Publication No.: US07705146B2Publication Date: 2010-04-27
- Inventor: Murray D. Bailey , Punit Bhardwaj , Pasquale Forgione , Elise Ghiro , Nathalie Goudreau , Teddy Halmos , Montse Llinas-Brunet , Marc-Andre Poupart , Jean Rancourt
- Applicant: Murray D. Bailey , Punit Bhardwaj , Pasquale Forgione , Elise Ghiro , Nathalie Goudreau , Teddy Halmos , Montse Llinas-Brunet , Marc-Andre Poupart , Jean Rancourt
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Agent Michael P. Morris; Mary-Ellen M. Devlin; Philip I. Datlow
- International Application: PCT/CA2005/000967 WO 20050622
- International Announcement: WO2006/000085 WO 20060105
- Main IPC: A61K31/535
- IPC: A61K31/535 ; C07D413/00 ; C07D401/00
Abstract:
The invention relates to compounds of formula (I) wherein R′, R2, R3, R4, R5, R6, Y, n and m are as defined herein. The compounds are useful for the treatment and prevention of hepatitis C viral infections in mammals by inhibiting HCV NS3 protease. The invention further relates to azalactone compounds of the formula (III) which can be reacted with an amide anion to produce the compounds of formula (I).
Public/Granted literature
- US20060258868A1 Hepatitis c inhibitor peptide analogs Public/Granted day:2006-11-16
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