Invention Grant
- Patent Title: Process for making phenoxy benzamide compounds
- Patent Title (中): 制备苯氧基苯甲酰胺化合物的方法
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Application No.: US11665247Application Date: 2005-10-11
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Publication No.: US07700640B2Publication Date: 2010-04-20
- Inventor: Philip Cornwall , David Simon Ennis , Melvyn Edward Giles , Jacob Robert James Perkins , Shelly Louise Jenkin , Jeremy Stephen Parker , Bharti Patel
- Applicant: Philip Cornwall , David Simon Ennis , Melvyn Edward Giles , Jacob Robert James Perkins , Shelly Louise Jenkin , Jeremy Stephen Parker , Bharti Patel
- Applicant Address: SE Sodertalje
- Assignee: AstraZeneca AB
- Current Assignee: AstraZeneca AB
- Current Assignee Address: SE Sodertalje
- Agency: Morgan, Lewis & Bockius LLP
- Priority: GB0423042.1 20041016; GB0502963.2 20050212
- International Application: PCT/GB2005/003882 WO 20051011
- International Announcement: WO2006/040527 WO 20060420
- Main IPC: A61K31/415
- IPC: A61K31/415 ; C07D231/38

Abstract:
A process for making a compound of formula (I), said process comprising a) reacting a compound of formula (II) with: i) a compound of formula (III) by nucleophilic aromatic substitution of X2 and ii) a compound of formula (IV) for example by nucleophilic aromatic substitution b) where necessary, converting X1 to a carboxylic acid; and c) coupling of the carboxylic acid group to an appropriate heterocyclic amine; wherein all variables are as defined in the description.
Public/Granted literature
- US20080200694A1 Process for Making Phenoxy Benzamide Compounds Public/Granted day:2008-08-21
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