Invention Grant
- Patent Title: Compounds for the treatment of AIDS and other viral diseases
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Application No.: US11089157Application Date: 2005-03-24
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Publication No.: US07674829B2Publication Date: 2010-03-09
- Inventor: Eliahu Kaplan
- Applicant: Eliahu Kaplan
- Applicant Address: IL Tel-Aviv
- Assignee: Novaremed Limited
- Current Assignee: Novaremed Limited
- Current Assignee Address: IL Tel-Aviv
- Agency: Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.
- Agent Ivor R. Elrifi; Jennifer L. Loebach
- Main IPC: A61K31/165
- IPC: A61K31/165 ; C07C233/16

Abstract:
The present invention provides methods for treating Acquired Immunodeficiency Syndrome (AIDS) and other viral diseases and Human Immunodeficiency Virus (HIV) related infections by administering one or more compounds of formula I: wherein: the dotted line represents a single or a double bond; and R1 and R2 are the same or different and independently of each other represent —CH2OH, —CH2OR4, —CH(OH)CH3, —CH(OR4)CH3 or a group represented by the formula: or salts or hydrates thereof in a carrier which minimizes micellar formation or van der Waals attraction of molecules of said compound. The invention also provides S enantiomeric forms of such compounds which possess the ability to inhibit cell growth whilst being of low toxicity to such cells and methods of making such compounds.
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