Invention Grant
US07674802B2 N-linked aryl heteroaryl inhibitors of LTA4H for treating inflammation
失效
用于治疗炎症的LTA4H的N-连接的芳基杂芳基抑制剂
- Patent Title: N-linked aryl heteroaryl inhibitors of LTA4H for treating inflammation
- Patent Title (中): 用于治疗炎症的LTA4H的N-连接的芳基杂芳基抑制剂
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Application No.: US11462263Application Date: 2006-08-03
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Publication No.: US07674802B2Publication Date: 2010-03-09
- Inventor: Vincent Sandanayaka , Jasbir Singh , Lei Zhao , Mark E. Gurney
- Applicant: Vincent Sandanayaka , Jasbir Singh , Lei Zhao , Mark E. Gurney
- Applicant Address: IS Reykjavik
- Assignee: deCODE genetics, ehf
- Current Assignee: deCODE genetics, ehf
- Current Assignee Address: IS Reykjavik
- Agency: Heslin Rothenberg Farley & Mesiti P.C.
- Main IPC: A61K31/454
- IPC: A61K31/454 ; A61K31/416 ; C07D403/02 ; A61K31/4035
Abstract:
The present invention relates to a chemical genus of biaryl nitrogen-attached heterocycles that are inhibitors of LTA4H (leukotriene A4 hydrolase). The compounds have the general formula: They are useful for the treatment and prevention and prophylaxis of inflammatory diseases and disorders.
Public/Granted literature
- US20070142434A1 N-LINKED ARYL HETEROARYL INHIBITORS OF LTA4H FOR TREATING INFLAMMATION Public/Granted day:2007-06-21
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