- Patent Title: Pyrimidine derivatives for the treatment of abnormal cell growth
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Application No.: US12059889Application Date: 2008-03-31
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Publication No.: US07674796B2Publication Date: 2010-03-09
- Inventor: John Charles Kath , Michael Joseph Luzzio
- Applicant: John Charles Kath , Michael Joseph Luzzio
- Applicant Address: US NY New York
- Assignee: Pfizer Inc.
- Current Assignee: Pfizer Inc.
- Current Assignee Address: US NY New York
- Agent Jeffrey H. Tidwell; Stephen D. Prodnuk; Suzanne M. Bates
- Main IPC: C07D401/14
- IPC: C07D401/14 ; C07D403/14 ; A61K31/506 ; A61P35/00
Abstract:
The present invention relates to a compound of the formula 1 wherein R1-R4 are as defined herein. Such novel pyrimidine derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.
Public/Granted literature
- US20080182840A1 PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELL GROWTH Public/Granted day:2008-07-31
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