Invention Grant
- Patent Title: Process for the preparation of compounds having an ace inhibitory action
- Patent Title (中): 具有抑制作用的化合物的制备方法
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Application No.: US10556986Application Date: 2004-05-07
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Publication No.: US07671215B2Publication Date: 2010-03-02
- Inventor: Branko Jenko
- Applicant: Branko Jenko
- Applicant Address: SI Ljubljana
- Assignee: Lek Pharmaceuticals, d.d.
- Current Assignee: Lek Pharmaceuticals, d.d.
- Current Assignee Address: SI Ljubljana
- Agency: Arent Fox LLP.
- Priority: SI200300123 20030516
- International Application: PCT/SI2004/000021 WO 20040507
- International Announcement: WO2004/101515 WO 20041125
- Main IPC: C07D207/00
- IPC: C07D207/00 ; C07D209/42
Abstract:
The present invention relates to the process for the preparation of compounds of formula (I) having an ACE inhibitory action wherein carboxy group of stereospecific amino acid is activated with an uranium salt in the presence of an aprotic solvent and an activated amino acid is further transformed with appropriate amine into ACE inhibitor or its precursor.
Public/Granted literature
- US20070072919A1 Process for the preparation of compounds having an ace inhibitory action Public/Granted day:2007-03-29
Information query
