Invention Grant
US07670844B2 Supported molecular biofluid viscosity sensors for in vitro and in vivo use
失效
支持用于体外和体内使用的分子生物流体粘度传感器
- Patent Title: Supported molecular biofluid viscosity sensors for in vitro and in vivo use
- Patent Title (中): 支持用于体外和体内使用的分子生物流体粘度传感器
-
Application No.: US11039076Application Date: 2005-01-20
-
Publication No.: US07670844B2Publication Date: 2010-03-02
- Inventor: Mark A. Haidekker , Sheila Grant , Emmanuel Theodorakis , Marcos Intaglietta , John A. Frangos
- Applicant: Mark A. Haidekker , Sheila Grant , Emmanuel Theodorakis , Marcos Intaglietta , John A. Frangos
- Applicant Address: US MO Columbia US CA Oakland US CA La Jolla
- Assignee: The Curators of the University of Missouri,The Regents of the University of California,La Jolla Bioengineering Institute
- Current Assignee: The Curators of the University of Missouri,The Regents of the University of California,La Jolla Bioengineering Institute
- Current Assignee Address: US MO Columbia US CA Oakland US CA La Jolla
- Agency: Greer, Burns & Crain, Ltd.
- Main IPC: G01N33/00
- IPC: G01N33/00

Abstract:
A device and a method for measuring viscosity that includes attaching molecular rotors to a solid surface, exposing the solid surface to a fluid having a viscosity to be measured, and taking optical measurements to determine viscosity. The solid surface is preferably quartz, polystyrene or silicate glass, such as a fiber optic probe or a glass cuvette. The molecular rotors are of the type that includes an electron-donor group and electron-acceptor group that are linked by a single bond so that the groups may rotate with respect to one another, and that exhibit a fluorescence emission when rotation is hindered.
Public/Granted literature
- US20060084177A1 Supported molecular biofluid viscosity sensors for in vitro and in vivo use Public/Granted day:2006-04-20
Information query