Invention Grant
- Patent Title: Tumor suppressor pathway in C. elegans
- Patent Title (中): 秀丽隐杆线虫的肿瘤抑制途径
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Application No.: US11973006Application Date: 2007-10-04
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Publication No.: US07670778B2Publication Date: 2010-03-02
- Inventor: H. Robert Horvitz , Ewa M. Davison , Xiaowei Lu
- Applicant: H. Robert Horvitz , Ewa M. Davison , Xiaowei Lu
- Applicant Address: US MA Cambridge
- Assignee: Massachusetts Institute of Technolgoy
- Current Assignee: Massachusetts Institute of Technolgoy
- Current Assignee Address: US MA Cambridge
- Agency: Clark & Elbing LLP
- Agent Kristina Bieker-Brady
- Main IPC: C12Q1/68
- IPC: C12Q1/68

Abstract:
The invention provides novel lin-8, lin-56, and lin-61 genes and polypeptides involved in cell fate determination and in cell proliferation. In addition, the invention includes mutants of these three genes, as well as methods for utilizing these genes, and their encoded polypeptides, in diagnosing and treating abnormal cell proliferation.
Public/Granted literature
- US20080213777A1 Tumor suppressor pathway in C. elegans Public/Granted day:2008-09-04
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