A system of manufacturing a custom set of pre-manufactured upper and lower dentures is provided. In one form, a set of master upper and lower dentures is created. The master upper and lower dentures are used to create reusable upper and lower dental matrices, respectively. These re-usable upper and lower dental matrices are repeatedly used to manufacture upper and lower pre-manufactured or standard sized dentures, respectively. Optionally, a dental patient can have these upper and lower pre-manufactured dentures custom fit or relined to fit the dental patient's mouth to form upper reline and/or lower reline pre-manufactured dentures. The dental patient can have custom fit dentures in two visits with the dentist, even two visits in the same day.