Invention Grant
- Patent Title: Morphinan derivatives, the quaternary ammonium salts thereof substituted in position 14, method for production and use thereof
- Patent Title (中): 吗啡衍生物，其在第14位取代的季铵盐，其制备方法及用途
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Application No.: US11899585Application Date: 2007-09-06
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Publication No.: US07655671B2Publication Date: 2010-02-02
- Inventor: Helmut Schmidhammer , Mariana Spetea , Johannes Schutz , Elisabeth Greiner , Falko Schüllner , Bettina Sailer , Kurt Stübegger
- Applicant: Helmut Schmidhammer , Mariana Spetea , Johannes Schutz , Elisabeth Greiner , Falko Schüllner , Bettina Sailer , Kurt Stübegger
- Applicant Address: AT Innsbruck
- Assignee: Alcasynn Pharmaceuticals GmbH
- Current Assignee: Alcasynn Pharmaceuticals GmbH
- Current Assignee Address: AT Innsbruck
- Agency: Cohen Pontani Lieberman & Pavane LLP
- Priority: DE10229842 20020703
- Main IPC: A61K31/485
- IPC: A61K31/485 ; C07D489/08
Abstract:
The present invention relates to a class of morphinan compounds and quaternary ammonium salts thereof, substituted in Position 14, which may be used as highly active analgesics or also as opioid antagonists. The present invention also relates to the pharmaceutically acceptable salts and easily produced derivatives thereof, a process for the production thereof and use thereof in the production of pharmaceutical specialities.
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