Invention Grant
- Patent Title: Methods and compositions for identifying anti-HCV agents
- Patent Title (中): 用于鉴定抗HCV药物的方法和组合物
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Application No.: US11844993Application Date: 2007-08-24
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Publication No.: US07655419B2Publication Date: 2010-02-02
- Inventor: Jeffrey Glenn , Ella Sklan , Kirk A. Staschke , Tina Myers Oakes
- Applicant: Jeffrey Glenn , Ella Sklan , Kirk A. Staschke , Tina Myers Oakes
- Applicant Address: US CA Palo Alto US IN Indianapolis
- Assignee: The Board of Trustees of the Leland Stanford Junior University,Eli Lily and Company
- Current Assignee: The Board of Trustees of the Leland Stanford Junior University,Eli Lily and Company
- Current Assignee Address: US CA Palo Alto US IN Indianapolis
- Agency: Bozicevic, Field & Francis, LLP
- Agent Carol L. Francis
- Main IPC: G01N33/53
- IPC: G01N33/53 ; A61K39/29
Abstract:
The invention features methods and compositions for screening for agents that modulate replication of a virus, particularly Flaviviridae virus (particularly hepatitis C virus (HCV)), where the methods provide for detection of agents that modulate the binding of TBC and NS5A, the inhibition of TBC activity, inhibition of Rab1 activity, and/or the expression of the TBC protein and/or Rab1 protein. The invention also features methods of controlling viral replication, and agents useful in such methods.
Public/Granted literature
- US20080261906A1 METHODS AND COMPOSITIONS FOR IDENTIFYING ANTI-HCV AGENTS Public/Granted day:2008-10-23
Information query
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