Invention Grant
- Patent Title: Methods of expanding stem and progenitor cells and expanded cell populations obtained thereby
- Patent Title (中): 从而获得的茎和祖细胞和扩大的细胞群扩大的方法
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Application No.: US12070543Application Date: 2008-02-19
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Publication No.: US07655225B2Publication Date: 2010-02-02
- Inventor: Tony Peled , Avi Treves , Oren Rosen
- Applicant: Tony Peled , Avi Treves , Oren Rosen
- Applicant Address: IL Jerusalem
- Assignee: Gamida Cell, Ltd.
- Current Assignee: Gamida Cell, Ltd.
- Current Assignee Address: IL Jerusalem
- Agency: Mintz, Levin, Cohn, Ferris, Glovsky and Popeo P.C.
- Agent Ivor R. Elrifi, Esq.; Matthew Pavao, Esq.
- Main IPC: A01N63/00
- IPC: A01N63/00 ; A61K35/26 ; A61K35/28 ; C12N5/08 ; C12N5/00
Abstract:
Ex vivo and in vivo methods of expanding a population of stem and/or progenitor cells, while at the same time reversibly inhibiting differentiation of the stem and/or progenitor cells by providing the stem and/or progenitor cells with an effective amount of at least one copper chelate, so as to maintain a free copper concentration available to said cells substantially unchanged, to thereby expand the population of said stem and/or progenitor cells, while at the same time reversibly inhibit differentiation of said stem and/or progenitor cells.
Public/Granted literature
- US20080279828A1 Methods of expanding stem and progenitor cells and expanded cell populations obtained thereby Public/Granted day:2008-11-13
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