Invention Grant
![Octahydropyrano[3,4-C]pyrrole tachykinin receptor antagonists](/docs/US/2010-01-26/US07652058B2/abs.jpg.600x600.jpg)
- Patent Title: Octahydropyrano[3,4-C]pyrrole tachykinin receptor antagonists
- Patent Title (中): 八氢吡喃[3,4-C]吡咯速激肽受体拮抗剂
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Application No.: US11792514Application Date: 2005-12-12
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Publication No.: US07652058B2Publication Date: 2010-01-26
- Inventor: Robert J. DeVita , Jinlong Jiang , Sander G. Mills , Jonathan R. Young
- Applicant: Robert J. DeVita , Jinlong Jiang , Sander G. Mills , Jonathan R. Young
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Yong Zhao; Valerie J. Camara
- International Application: PCT/US2005/044822 WO 20051212
- International Announcement: WO2006/065711 WO 20060622
- Main IPC: A61K31/407
- IPC: A61K31/407 ; C07D491/052
![Octahydropyrano[3,4-C]pyrrole tachykinin receptor antagonists](/abs-image/US/2010/01/26/US07652058B2/abs.jpg.150x150.jpg)
Abstract:
The present invention is directed to certain hydropyranopyrrolidine compounds which are useful as neurokinin-1 (NK-1) receptor antagonists, and inhibitors of tachykinin and in particular substance P. The invention is also concerned with pharmaceutical formations comprising these compounds as active ingredients and the use of the compounds and their formulations in the treatment of certain disorders, including emesis, urinary incontinence, depression, and anxiety.
Public/Granted literature
- US20080108689A1 Octahydropyrano[3,4-C]Pyrrole Tachykinin Receptor Antagonists Public/Granted day:2008-05-08
Information query
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