Invention Grant
US07651838B2 Prenatal diagnosis method on isolated foetal cell of maternal blood
有权
母亲血液分离胎儿细胞产前诊断方法
- Patent Title: Prenatal diagnosis method on isolated foetal cell of maternal blood
- Patent Title (中): 母亲血液分离胎儿细胞产前诊断方法
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Application No.: US10695744Application Date: 2003-10-30
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Publication No.: US07651838B2Publication Date: 2010-01-26
- Inventor: Patrizia Paterlini-Brechot
- Applicant: Patrizia Paterlini-Brechot
- Applicant Address: FR Paris FR Paris FR Paris
- Assignee: Institut National de la Sante et de la Recherche Medicale,Assistance Publique-Hopitaux de Paris,Universite Rene Descartes Paris 5
- Current Assignee: Institut National de la Sante et de la Recherche Medicale,Assistance Publique-Hopitaux de Paris,Universite Rene Descartes Paris 5
- Current Assignee Address: FR Paris FR Paris FR Paris
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: FR0105824 20010430
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12P19/34 ; G01N33/53
Abstract:
The invention concerns a novel non-invasive prenatal diagnostic method implemented with a sample of maternal blood. Said method enables prenatal diagnosis on isolated non-apoptotic epithelial foetal cells of maternal blood after they have been enriched by filtration, morphologically or immunologically and genetically analysed. Said method is advantageous in that it is perfectly harmless for the mother and the foetus and provides a highly sensitive and specific diagnosis. It enables early detection of a genetic or chromosomal abnormality of the foetus, of a genetic or infectious (viral, bacterial or parasitic) pathology of the foetus, of accurate genotype, and in particular of the genetic sex of the foetus.
Public/Granted literature
- US20050049793A1 Prenatal diagnosis method on isolated foetal cell of maternal blood Public/Granted day:2005-03-03
Information query
