Invention Grant
- Patent Title: Acetyl 2-hydroxy-1, 3-diaminoalkanes
- Patent Title (中): 乙酰基2-羟基-1,3-二氨基烷烃
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Application No.: US11447789Application Date: 2006-06-06
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Publication No.: US07645780B2Publication Date: 2010-01-12
- Inventor: Varghese John , Michel Maillard , James P. Beck , Eric T. Baldwin , Robert Hughes , Shon R. Pulley , Ruth T. TenBrink
- Applicant: Varghese John , Michel Maillard , James P. Beck , Eric T. Baldwin , Robert Hughes , Shon R. Pulley , Ruth T. TenBrink
- Applicant Address: US CA South San Francisco
- Assignee: Elan Pharmaceuticals, Inc.
- Current Assignee: Elan Pharmaceuticals, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- Main IPC: C07D213/56
- IPC: C07D213/56 ; A61K31/44
Abstract:
Disclosed are compounds of the formula: where variables Z, X, R15, R2, R3, and Rc are defined herein. Compounds disclosed herein are inhibitors of the beta-secretase enzyme and are therefore useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal.
Public/Granted literature
- US20070293483A1 Acetyl 2-hydroxy-1, 3-diaminoalkanes Public/Granted day:2007-12-20
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