Invention Grant
US07645769B2 Inhibitors of c-Jun N-terminal kinases for the treatment of neurodegenerative disorders relating to apoptosis and/or inflammation
有权
用于治疗与凋亡和/或炎症相关的神经变性疾病的c-Jun N-末端激酶抑制剂
- Patent Title: Inhibitors of c-Jun N-terminal kinases for the treatment of neurodegenerative disorders relating to apoptosis and/or inflammation
- Patent Title (中): 用于治疗与凋亡和/或炎症相关的神经变性疾病的c-Jun N-末端激酶抑制剂
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Application No.: US11499334Application Date: 2006-08-04
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Publication No.: US07645769B2Publication Date: 2010-01-12
- Inventor: Afzal Khan , Darren Peter Medland , Gurpreet Singh Bhatia
- Applicant: Afzal Khan , Darren Peter Medland , Gurpreet Singh Bhatia
- Applicant Address: JP
- Assignee: Eisai R & D Management Co., Ltd.
- Current Assignee: Eisai R & D Management Co., Ltd.
- Current Assignee Address: JP
- Agency: Wilmer Cutler Pickering Hale & Dorr LLP.
- Priority: GB0516156.7 20050805
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61K31/4375

Abstract:
The present invention provides novel compounds of formula I and their use in the inhibition of c-Jun N-terminal kinases. The present invention further provides the use of these compounds in medicine, in particular in the prevention and/or treatment of neurodegenerative disorders related to apoptosis and/or inflammation.
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